Toxic Substances Control Act (TSCA) Science Advisory Committee on Chemicals (SACC) - Review of Risk Evaluation for Trichloroethylene

Filed on regulations.gov — full text not in the inline record.

The comments of the Chemical Products and Technology Division of the American Chemistry Council on the Draft Risk Evaluation for trichloroethylene are attached. Steve Risotto American Chemistry Council

Attached are follow-up comments from the American Chemistry Council on the SACC's discussion of the draft TCE risk evaluation

Filed on regulations.gov — full text not in the inline record.

Filed on regulations.gov — full text not in the inline record.

The attached comments deal with cardiac malformations, including the discussion relating to the Johnson et al (2003) study, the Charles River Laboratories (2019) study, and the publication based on that study (DeSesso et al, 2019). The comments are being submitted on behalf of the American Chemistry Council and the Halogenated Solvents Industry Alliance.

The comments of the Chemical Products and Technology Division of the American Chemistry Council on the Draft TCE Risk Evaluation are attached.

Attached are comments from ToxStrategies on the USEPA's Draft TSCA TCE Risk Evaluation for the consideration of the Science Advisory Committee on Chemicals (SACC). The comments are focused on and critique the systematic review process employed by the Agency in the development of the Draft TCE Risk Evaluation. While the USEPA did not include any charge questions specific to the application of their systematic review approach for the SACC to consider, given both the mandate under TSCA to utilize systematic review and the fact that the application of their systematic review approach is the foundation of the risk evaluation, we strongly encourage the SACC to consider what we believe are critical comments concerning the Agency's systematic review approach as applied in the TCE risk evaluation. These comments are made on behalf of the American Chemistry Council.